SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec24458fad1bc71aba1b48a4e5fb2a8bf8f838229c87e05bd8c8200a9512b074' 
  AND token = 'P8w4XQl6wVZ27UAFU1g8qEB/0x7p1n4thLxN+T830EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}