SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746500bf95a11d80d03ff0a8ef87f26fc61bb6748d2573e9e6bbc60d7aeae5e4' 
  AND token = '848Hny/2UyMXM46P0M216PWYrIRqX/BEPn996rH2NUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}