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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d62d0641423f77f42980327979e174b02d4a3ecca3ec3990d78579ff7ec3622' 
  AND token = 'P5qc5INCPoCrPMUlqt3ZyXQz22mWxJKVuytl1D4BAV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}