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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657f4372c0185cc80e822898d5550e179bbd5be87dc883d86952e48a43d62d27' 
  AND token = 'tyIqF2C4WVZRvl5LQGN8OkjHelfe+U1gAHbbhqGsAIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}