SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2abed694152fce69e93d65a3625c1f91bc1caf9c9a82a4cdc7e988cd8a862a9b' 
  AND token = 'R+U6eqA6YdEKZtWSzaEE5OU7ifhaU9c31ZfYOnV8Lfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}