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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '717c706b0baa0ea81ed3f3f8453ad995d7d84efa2c319413a0f353183ffcc49b' 
  AND token = 'i/eW+n7pzcBwwirM/nMsW6W6XG6kMGUVch6Cpa1tvTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}