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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f2e05846e512b58271ac2450b59bf687cb2ea64e4858d2d2f055c741f348b2' 
  AND token = 'cVXTlqKvzVoTA18MzJNRUxCHzyLZ4MqQa2VKToH4Vvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}