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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ac4495a016f80095fac378d1a2e404c21581c4e35b8fe51b85747304b66c3b7' 
  AND token = 'F/u6PzhzhXEa09zneU31OA3sn0+GzUox+mHYjYtkSnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}