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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de29a146f4ed67f29c07c05b2214b035f4d1ceb4d3dbc8811fbb523aaea8546' 
  AND token = 'kWEWtguiitnV3HDyVPX/Xp0+lYZjI2YTxdHThcBHYDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}