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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880f6afcfbb25ad2f68a3f1e5dae40b72991ae744ed4104f27dfb8abb0936c4a' 
  AND token = 'JkUbwlPeVHzKRMBxWgft4wl8rXT40goQD4kUDkXGohs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}