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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb375002170df76437f8de505473ce1a303f5dd32d5b8a9f9007bbb94cbe4f1e' 
  AND token = 'X1xksvHYfzG6kfBxBaENjwvl5BI1OEgqvYMZcSCn5hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}