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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4291122eeb29cb4b174c9d8738e45aa6c2db2357592d0974c55d302921fd0c76' 
  AND token = 'j+L11jQ92uEL83nDt7uj/zT4ol86Mu95twqsKDUWbbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}