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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '247d11cb09c3b9811ae862ce7c63515d3d3e7c24cf8b77aab374e77a182d3890' 
  AND token = '+2sGH2DcD9DSCTOn3Yv7z5n0Rt+F1S7UjD6OCmeb270=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}