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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfdd9a4bdcc6bb2a0849b1bdcd6072c201cd1b26e72cede957e5caf2fefd7a77' 
  AND token = 'PwC6oI46v/aSJ4cBbMJYY7knRdI1MYb1q6uGN38wY5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}