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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39322728cae11044873f03bf2d3664dd6b057fe94e22609b3ad03650d4b381f6' 
  AND token = 'KRQqIZCf1/FiHdAIk0WhUTIVqDZ3DzBM/f6y++fDbSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}