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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3b76c7a6196cf657e8fb3cbd4419d94af64e14870057761aa224d80527f3ac' 
  AND token = '+bsT2+gOrTKPr5gHSbuHNNVrjiEOFXAGpMCFs4IVl3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}