SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68fd75ada152375724a2af87fc88e078ff3930b8c1bba2981f843df3f5e657f5' 
  AND token = 'E5j9SpGsA0xnugp3bxMfL+ZYsvUT4/jwQj4w25NSImQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}