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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5f0fa5376433ee6b1a3c054ed0872961ea96da980d1fe2a57c9f2561f35f5d' 
  AND token = 'IcP5FaOSSGQHBS0bM/zRAATcLXDaMjL5Anvm6EZI6TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}