SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb40648704528d9aaf4a7b05ea0bba863cd4619472af7ebc13c11e0178a8dc00' 
  AND token = 'EeGRovaqnvw2nWF0bD+o4fAAX7rvhx6k/F1JDWFEerA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}