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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eff70499b0c55fd4159ff5ecf55c08c9a78fec1b0a3e669489c291d657ae3cd' 
  AND token = 'p//Sphg32z+NRDoKYJ5H/OkoVagMIdjzTHyLA9Ca7LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}