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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a9d84e8b8eebe5a2d0fbe5d8be0b8241024583a9dc76989f1f0436410d82a86' 
  AND token = '2mi28ckgIUNUGTRjrbrPuDi8hM+XrjY1ZZDV0pFTp4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}