SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c6dce2cd45a0b842a0cc4b91ffa7a8283eda27133509d97521bdcfc90bcbdbf' 
  AND token = '/8GJsphIOWzZkXc2QcPQjxo5i2bZ4KYZiqE5ObSLWug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}