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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ffa9739204b1f3a8c2b5b905a2148bac6effb8bed48f13fa46a94ea6b0d8fa9' 
  AND token = 'vo/03/K6So2HGkDC/wh4MUfMu64ESXhJuI5t7+YM+vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}