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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3648e7812d459697626c04ba341f43d49d268a0e3159f3f61e09cb762123e58b' 
  AND token = 'D2HLZSwC080wkZ7pctVGzDCSymVt0ga2ePFa1CEgx6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}