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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1cf03ee19f81dc47596bf7b7ec2f01770febc2cecdcc13488780c2e301ec63' 
  AND token = 'C+gglj/pAFZoTo0oLBL/O0wA3eLjU24gKM6O0Ben1G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}