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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c76d9381f1dd3040eee39e6a672ab628e620161c04613338bea35abcde9ba83e' 
  AND token = 'uHtxY+qLPXMWnfx3OZ+Z9T3cStghzgvOMIzik7V0Mwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}