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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4b6026e5fc49e6d0b9ee04856b45ab34c5a4b331b16b4233e08f23c57dd591' 
  AND token = 'zMBvrqJsnOLNc1wQciV1yqX3jyn89Z6ZRdSHlgfgwR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}