SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22dc960f2a6e67f8f47aec70b59e834e7112cdc1841c11190077e49afd676f97' 
  AND token = '0Ztm8/1QPWhhnQuptPVI9ncKyATX1kWs6ZhnmcZ/h9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}