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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de779a8e3c8ee7b393018cc74cbbf26188252642df4078620bc76edac210165' 
  AND token = 'SptAeH2K8kf1lYO6kY05ScJ4lKlI4a0AmTjv02/noVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}