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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd328f0530108e6e1d11a864e72ae7e21f84934bba526129d95ee07857f74e303' 
  AND token = 'LrrXiUC9ZDrHZCGV1Zdd0/6GdzwilO5L7YgXXB22hYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}