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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7f6e267ee9543c3a3f890f5be2d4e38908d0058b6e1e1fe1335bebf0ea3f96' 
  AND token = 'IkSlZIa0uH6PfxOoRHbH1KffQ0tVal3Yjn1kzlU2PL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}