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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a0895b4419b5879d65f9b5c7b252bfa4dd60b24c1e667d0901d1320548dd077' 
  AND token = 'rdCBPjAI2Nq3BaAsCB9lOIDe01JqM5+ahBIgqYr5sqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}