SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c050b3adb369b62148ebaa68092b91c71dea3a9c765c2f4b32c899d7b68cb7d' 
  AND token = '1MGOKK2OAQLYaw4Cbuqtstrywd39vuo0VTdozEzOw4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}