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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c210816752883d5cdb881de2ea403c71ba60e6e7977a6d3502e7cc47228560' 
  AND token = '61qHMzrRYEQ8nMggfHOp0HDN9rqtxwSZ1ZuNHnLHv+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}