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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bab702680519ea236f6fcee275e1b6d1aa5d34809ac517aa25f0833bb4d6c223' 
  AND token = 'lOKPerv4qPMPA3qdDy2tvWU+GyUtgeMS4sf05ZavLp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}