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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efbc339f802f6191224e94aa8d88d5c99c0e25e16a6bede497892ef611b30a4' 
  AND token = 'O+jl2RN19Mhweog9g7K31qcwVVvbZXDsYy9HqOeFTmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}