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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8b463af5b30e527fae5aa7ffe1e1291e36af44a23396236a6f50827bea6b92' 
  AND token = '/6LtdGyN/ponKUczrDa7di1d+UWWuVSgShbq7XYjeJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}