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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b305f214da8b2e8b8fdf05c9645f428063a75a38dcda95766da5d0b1703dad9a' 
  AND token = 'is0TKL95E2MfXvRpapC2Q6bHn5YEu++rN53WKJBnQ7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}