SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4979055be22ac5716412613a1a2dcee2b7379b91f591ad4e071dfc6995154f77' 
  AND token = 'Cdwan71e2y0dqiqfCGWKx8jDESNm1SOHMtVYyskx9Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}