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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '410f758f19ebbd03a6a37c44aee493d5f0c0038dc74587476668a74fa8281b0c' 
  AND token = 'B1rxniB7ZD6emzmiFloL/b1VJYz/rywkRgdZewUO3EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}