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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19573c333d5dac5c72d267d4637f4f60d0dcbb3280fd517547423f43726f811b' 
  AND token = 'nSdr41eUSrCxcQrKkK8ng5btpHgnOfi3mgafAOQe5AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}