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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67e9ea39e91f0d845c2aaef665e0147b54014abf9c5a14b069ea525d28f1974' 
  AND token = 'XpCMOkNTzQ6J5RV4sGFTEalpBOu0B5NXNNiOh2RL3LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}