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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9315ceb99435786ed9414dacf034c5cdd8ba9d835663d19aac82d3613694b4a6' 
  AND token = 'HDwyWhEcQpMYD1/w1JiTiDwA5yxLE4p/E2ugjsykO5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}