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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '760306a2fee0b281e6b0cc9d4d95fbb57cacd59530778123194ff5f9a01d968a' 
  AND token = '9WD68FHwWPw416tiliS2JcJMHaCtgEzifUH+r4L2Jks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}