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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b73401930d77988069a3c6bb31e9708cd2036b35247004b7a39222a99904881' 
  AND token = 'F5SOASEroUuwZO1TjrQAndp+JiJ8caoWFHxIJkn8tQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}