SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd2056af13b4f6be42f760597de4ee481dbbf43fc3ca13a381b9baf70b907c3' 
  AND token = 'vT5xYML6Rpm4f8V2I6arCio5d6V0SyITrrY7OxA7dgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}