SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949ffa6cc9f8f2bc486644a2d1d0482134b38b0834b80502713f81fb1c62dfeb' 
  AND token = 's2Kzj5Pe1PB3kGfNUbq/efDJuzZoMAvCF7POl1XWymM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}