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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d41d4aa8c1f1992f713868db7c2afb29482de0d4a9c44c4d0ad94963684627d' 
  AND token = 'fsZrSLGXhx5P/v+U3mmLObJT66vROfhEGMrnyBoRd1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}