SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd0026bc84a952153e79bb47cb726749b0ca4c8e4f3c8ccee09742b4bfe5e27' 
  AND token = '4hyB535Udkc4bpoVtcY7O5DcV7Um3RpR2jC2R50pFik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}