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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f3d58ef3808a7081cf3deddb4ace1c3d90782c2f3acafcc194d019d2856afff' 
  AND token = 'j/C1HnNudsvRYRlIN/gssvvusaZ/FvNtOx5LI0JZG4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}